About ARS

The catalyst for the ARS Program was the partnership between infectious disease and clinical pharmacy experts who sought to improve antibiotic utilization at their hospital. Their approach of physician education and real time pharmacy intervention proved superior to strict formulary restrictions. The steps and interventions created a synergistic relationship between pharmacy, infectious disease and microbiology. The ARS management group continues to develop and evolve the program, redefining the breadth and depth of what a successful antimicrobial stewardship program delivers.


Dr. Cheatham received his Bachelor of Science in Pharmacy and Doctor of Pharmacy from Butler University in 1999 and 2000. He then completed a pharmacy practice residency and a specialty residency in Infectious Diseases at IU Health in Indiana. Dr. Cheatham has practiced at St. Francis Hospitals and Health Centers in Indianapolis for the past seven years. He established an antimicrobial management program focused on optimal antimicrobial utilization, improved patient outcomes, and the prevention of resistance. The program has been successful in allowing for a collaborative practice between physicians, pharmacists, laboratory, and infection control practitioners. He has also been active in multiple areas of research including antimicrobial use, antimicrobial resistance, and optimizing antimicrobial utilization through pharmacokinetics and pharmacodynamics. The resulting research has led to additions to the scientific literature.


Dr. Smith received his BS and Doctor of Pharmacy from UNC Chapel Hill. He moved to Indianapolis to complete a pharmacy practice residency at Methodist Hospital of Indiana. Dr. Smith has spent the past 20 years working with infectious diseases physicians, fellow pharmacists, microbiology, and infection-control personnel at Indiana University Health (IU Health). The goal of these efforts is to contain bacterial resistance by studying antimicrobial utilization trends, surveying antimicrobial resistance patterns, and educating healthcare practitioners in optimal antimicrobial prescribing and infection-control practices. Dr. Smith established the only PGY2 infectious diseases pharmacy residency program in the state of Indiana. To date, 13 residents have completed the program. A flourishing research collaborative has been established with Dr. Michael Kays of Purdue University, which has led to multiple publications in the scientific press.

Matthew F. Wack, MD

Dr. Wack received his Medical Degree from the Medical College of Ohio. He completed his residency in internal medicine at Indiana University Medical Center and fellowship in Infectious Diseases from the University of Iowa Hospitals and Clinics. He has practiced Infectious Disease medicine and participated in research in both academic and private practice settings. He served as Co-chair of Infectious Disease at IU Health for 10 years, education director for Infectious Diseases at Methodist Hospital of IU Health, and Pharmacy and Therapeutics advisor at Methodist Hospital. He has also been active in developing hospital-based antimicrobial management programs in both private and academic practice settings. He has lectured both nationally and internationally on the topics of antimicrobial use and resistance.Dr. Wack and Dr. Smith have collaborated for over 18 years in developing programs to combat antimicrobial resistance in hospital settings. This has led to the training of 20 infectious disease pharmacists, multiple scientific publications, and cost savings for their member institutions that exceed $30 million.

Richard R. Yates, MD

Dr. Yates received his Medical Degree from Southwestern Medical School in Dallas, TX. He completed his internship and residency in internal medicine at Indiana University Medical Center in Indianapolis, IN. He then completed his fellowship in Infectious Diseases from University of Texas Health Science Center in San Antonio, TX. At Methodist Hospital in Indianapolis, he became Chairman of the Pharmacy and Therapeutics Committee. He also began his work with Dr. Smith in antimicrobial management, which has now expanded to multiple hospitals. Dr. Yates moved to Texas to begin an infectious disease practice. There he introduced the ARS Program including both acute care hospitals and long term acute care hospitals. Dr. Yates currently is chairman of the P & T committees at three hospitals. He served as Chief of Medicine at East Texas Medical Center for five years. He also serves on the critical care committee and the transplant committee.